Imidacloprid da Moxidectin Spot-on Solutions (don Dogs)

【Babban Sinadari】

Imidacloprid, Moxidectin

【Bayyanar】

Ruwan rawaya zuwa launin ruwan rawaya.

【Pharmacological mataki】

Antiparasitic magani.

Pharmacodynamics:Imidacloprid sabon ƙarni ne na maganin kwari na nicotine mai chlorinated. Yana da babban alaƙa ga masu karɓar nicotinic acetylcholine na postsynaptik a cikin tsarin kulawa na tsakiya na kwari, kuma yana iya hana ayyukan acetylcholine, wanda ke haifar da gurɓataccen gurɓataccen ƙwayar cuta da mutuwa. Yana da tasiri a kan ƙwanƙarar manya da ƙananan ƙuma a matakai daban-daban, kuma yana da tasirin kisa akan ƙananan ƙuma a cikin muhalli. Tsarin aikin moxidectin yana kama da na abamectin da ivermectin, kuma yana da kyakkyawan sakamako na kisa akan ƙwayoyin cuta na ciki da na waje, musamman nematodes da arthropods. Sakin butyric acid (GABA) yana ƙara ƙarfin daurin sa ga mai karɓa na postsynaptic, kuma tashar chloride yana buɗewa. Moxidectin kuma yana da zaɓin zaɓi da babban kusanci ga tashoshi na chloride mai tsaka-tsaki na glutamate, ta haka yana tsoma baki tare da watsa siginar neuromuscular, shakatawa da gurɓata ƙwayoyin cuta, wanda ke haifar da mutuwar parasites. Inhibitory interneurons da excitatory motor neurons a cikin nematodes su ne wuraren aikin sa, yayin da a cikin arthropods shi ne mahadar neuromuscular. Haɗuwa da su biyun yana da tasirin aiki tare.

Pharmacokinetics:Bayan gwamnati ta farko, imidacloprid an rarraba shi da sauri zuwa jikin kare a wannan rana, kuma ya kasance a cikin jiki yayin lokacin gudanarwa 4-9 kwanaki bayan gudanarwa, ƙwayar plasma na moxidectin a cikin karnuka ya kai matakin mafi girma, kuma shi ana rarraba a cikin jiki a cikin wata daya kuma a hankali a hankali kuma a cire shi.

【alamomi】
Domin rigakafi da maganin cututtuka na ciki da na waje a cikin karnuka. Rigakafin da kuma kula da cututtuka na ƙuma (Ctenocephalic canis), maganin ƙwayar cuta (Catonicus canis), maganin ciwon kunne (ltchy otica), sarcoids canine (Scabies mites), da demodicosis (Demodex canis), don maganin Angiostrongylus da cututtuka na gastrointestinal nematode (manyan manya, manya da balagagge da kuma L4larvae na Toxocara canis, Ancylostoma canis, da Ancylocephalus larvae; manya na Toxocara lionis da Trichocephala vixensis). Kuma za a iya amfani da a matsayin adjuvant magani na rashin lafiyan dermatitis lalacewa ta hanyar fleas.

【Amfani da sashi】
Amfani na waje, sauke wannan samfurin a kan fata daga bayan kare tsakanin kafada biyu zuwa gindi, kuma a raba shi zuwa wurare 3-4. Kashi ɗaya, na karnuka, da 1kg na nauyin jiki, 10mg na imidacloprid da 2.5mg na moxidectin, daidai da 0.1ml na wannan samfurin. A lokacin prophylaxis ortreatment, ana bada shawara don gudanarwa sau ɗaya a wata. Hana karnuka lasa.

【Tasirin gefe】

(1) A cikin mutum ɗaya, wannan samfurin na iya haifar da rashin lafiyar gida, haifar da itching na wucin gadi, mannewar gashi, erythema ko amai. Waɗannan alamun suna ɓacewa ba tare da magani ba.

(2) Bayan gudanarwa, idan dabbar ta lasa wurin gudanarwar, alamun cututtuka na wucin gadi na iya bayyana lokaci-lokaci, irin su tashin hankali, rawar jiki, alamun ido (alalibai, reflexes, da nystagmus), numfashi mara kyau, salivation, da Alamun kamar amai. ; canje-canjen halayen lokaci-lokaci kamar rashin son motsa jiki, jin daɗi, da asarar ci suna faruwa.

【Matakan kariya】

(1)Kada a yi amfani da ƙonawa a ƙasa da makonni 7. Karnukan da ke da rashin lafiyar wannan samfurin bai kamata su yi amfani da shi ba. Karnuka masu ciki da masu shayarwa yakamata su bi shawarar likitan dabbobi kafin amfani.

(2) Karnukan da ke ƙasa da 1kg dole ne su bi shawarar likitancin dabbobi yayin amfani da wannan samfur.

(3) Wannan samfurin ya ƙunshi moxidectin (macrocyclic lactone), don haka lokacin amfani da wannan samfurin a kan collies, tsofaffin karnuka na Turanci da nau'o'in da suka danganci, ya kamata a ba da kulawa ta musamman don hana waɗannan karnuka lasa.samfur da baki.

(4) Karnuka marasa lafiya da karnuka masu raunin jiki su bi shawarar likitocin dabbobi lokacin amfani da shi.

(5)Kada a yi amfani da wannan samfurin akan kuliyoyi.

(6)Lokacin da ake amfani da wannan samfurin, kar a bari magungunan da ke cikin bututun miyagun ƙwayoyi su tuntuɓi idanu da bakin dabbar da ake gudanarwa ko wasu dabbobi. Hana dabbobin da suka ƙare da magani daga lasar juna. Kada a taɓa ko gyara gashi har sai maganin ya bushe.

(7) Lokaci-lokaci 1 ko 2 bayyanar karnuka ga ruwa a lokacin lokacin gudanarwa ba zai tasiri tasirin maganin ba sosai. Koyaya, yawan amfani da shamfu don wanka ko jiƙa a cikin ruwa da karnuka na iya shafar ingancin maganin.

(8)Kiyaye yara daga hulɗa da wannan samfurin.

(9)Kada a ajiye sama da 30℃,kuma kar a yi amfani da abin da ya wuce ranar ƙarewar lakabin.

(10) Mutanen da ke fama da rashin lafiyar wannan samfurin kada su gudanar da shi.

(11) Lokacin gudanar da miyagun ƙwayoyi, mai amfani ya kamata ya guji hulɗa da fata, idanu da bakin wannan samfurin, kuma kada ku ci, sha ko shan taba; bayan gudanarwa, sai a wanke hannaye. Idan ya fantsama fata da gangan, a wanke da sabulu da ruwa nan da nan, idan ya fantsama cikin idon da gangan, a wanke da ruwa nan da nan.

(12) A halin yanzu, babu takamaiman magani na ceto don wannan samfur; idan an hadiye ta ta hanyar kuskure, gawayi mai kunna baki zai iya taimakawa lalata.

(13) Abubuwan da ke cikin wannan samfurin na iya gurɓata kayan kamar fata, masana'anta, robobi, da saman fenti. Kafin wurin gudanarwa ya bushe, hana waɗannan kayan tuntuɓar wurin gudanarwa

(14)Kada ka bar wannan samfurin ya shiga cikin ruwan saman.

(15)Ya kamata a zubar da magungunan da ba a yi amfani da su ba da kayan tattarawa ta hanyar da ba ta da lahani bisa ga bukatun gida.

【Janyewa  lokaci】Babu

【Ƙayyadaddun bayanai】

(1) 0.4ml: Imidacloprid 40mg +Moxidectin 10mg

(2) 1.0ml: Imidacloprid 100mg+Moxidectin 25mg

(3) 2.5ml: Imidacloprid 250mg +Moxidectin 62.5mg

(4)4.0ml: Imidacloprid 400mg+Moxidectin 100mg

 【Adana】

Rufewa, an adana shi a zafin daki.

【Rayuwar rayuwa】

shekaru 3