Babban sashi: Doxycycline hydrochloride

Kaddarori: Wannan samfurin kore ne mai haske.

Ayyukan Pharmacological:

Pharmacodynamics:Wannan samfurin shine tetracycline m-bakan maganin rigakafi tare da m-bakan antibacterial sakamako. Kwayoyin cututtuka sun haɗa da kwayoyin cutar Gram-positive kamar pneumococcus, streptococcus, wasu staphylococcus, anthrax, tetanus, corynebacterium da sauran kwayoyin cutar Gram kamar Escherichia coli, Pasteurella, Salmonella, Brucella da Haemophilus, Klebsiella da meliobacter. Hakanan zai iya hana Rickettsia, mycoplasma da spirochaeta zuwa wani ɗan lokaci.

Pharmacokinetics:Shanye cikin sauri, ƙarancin tasiri ta abinci, haɓakar bioavailability mai yawa. Ana kiyaye tasirin jini mai tasiri na dogon lokaci, ƙwayar nama yana da ƙarfi, rarraba yana da fadi, kuma yana da sauƙin shiga cikin tantanin halitta. Matsakaicin ƙarar da ke fitowa a cikin karnuka yana da kusan 1.5L/kg. Adadin daurin furotin mai girma ga karnuka 75% zuwa 86%. Wani sashi wanda ba ya aiki ta hanyar chelation a cikin hanji, kashi 75% na adadin kare an kawar da shi ta wannan hanyar. Fitar koda shine kusan kashi 25%, biliary excretion kasa da 5%. Rabin rayuwar kare yana kusan awanni 10 zuwa 12.

Mu'amalar magunguna:

(1) Lokacin da aka ɗauka tare da sodium bicarbonate, zai iya ƙara ƙimar pH a cikin ciki kuma ya rage sha da aikin wannan samfurin.

(2) Wannan samfurin zai iya samar da hadaddiyar giyar tare da divalent da trivalent cations, da dai sauransu, don haka idan aka sha da calcium, magnesium, aluminum da sauran antacids, kwayoyi masu dauke da baƙin ƙarfe ko madara da sauran abinci, za a rage shan su, wanda ya haifar da rage yawan ƙwayar magungunan jini.

(3) Yin amfani da iri ɗaya tare da magungunan diuretics masu ƙarfi kamar furthiamide na iya ƙara lalacewar koda.

(4) Zai iya tsoma baki tare da tasirin ƙwayoyin cuta na penicillin akan lokacin kiwo na kwayan cuta, yakamata a guji amfani da iri ɗaya.

Alamomi:

Kamuwa da cuta na m kwayoyin cuta, korau kwayoyin cuta da mycoplasma. Cututtuka na numfashi (mycoplasma pneumonia, chlamydia pneumonia, feline reshen hanci, cutar calicivirus feline, distemper canine). Dermatosis, tsarin genitourinary, kamuwa da cutar gastrointestinal, da dai sauransu.

Amfani da sashi:

Doxycycline. Don gudanar da ciki: kashi ɗaya, 5 ~ 10mg a kowace 1kg nauyin jiki don karnuka da kuliyoyi. Ana amfani dashi sau ɗaya a rana don kwanaki 3-5. Ko kuma kamar yadda likita ya umarta. Ana ba da shawarar shan bayan ciyarwa da shan ruwa mai yawa bayan an sha ruwa.

Gargadi:

(1) Ba a ba da shawarar karnuka da kuliyoyi kasa da makonni uku kafin haihuwa, lactation, da 1 watan haihuwa.

(2) Yi amfani da hankali a cikin karnuka da kuliyoyi masu tsananin hanta da rashin aikin koda.

(3) Idan kana buƙatar shan kayan abinci na calcium, abubuwan ƙarfe, bitamin, antacids, sodium bicarbonate, da dai sauransu a lokaci guda, don Allah a kalla tazara na 2h.

(4) An haramta amfani da diuretics da penicillin.

(5) Haɗe tare da phenobarbital da anticoagulant zai shafi aikin juna.

Mummunan halayen:

(1) A cikin karnuka da kuliyoyi, mafi yawan illolin doxycycline na baka sune amai, gudawa, da rage sha'awa. Don rage mummunan halayen, ba a sami raguwa mai yawa a sha na miyagun ƙwayoyi ba lokacin da aka sha da abinci.

(2) 40% na karnuka da aka kula da su sun karu a cikin enzymes masu alaka da aikin hanta (alanine aminotransferase, conglutinase na asali). Muhimmancin asibiti na haɓaka aikin hanta da ke da alaƙa da enzymes bai bayyana ba.

(3) Doxycycline na baka na iya haifar da jijiyar hanji a cikin kuliyoyi, kamar allunan baka, yakamata a sha da ruwa akalla 6ml, ba bushewa ba.

(4) Yin jiyya tare da tetracycline (musamman na dogon lokaci) na iya haifar da haɓakar ƙwayoyin cuta marasa hankali ko fungi (cututtuka biyu).

Manufar: Kawai don kuliyoyi da karnuka.

Bayani: 200mg/ kwamfutar hannu